Structure of bacterial phospholipid transporter MlaFEDB with substrate bound

In double-membraned bacteria, phospholipid transport across the cell envelope is critical to maintain the outer membrane barrier, which plays a key role in virulence and antibiotic resistance. An MCE transport system called Mla has been implicated in phospholipid trafficking and outer membrane integ...

Full description

Bibliographic Details
Main Authors: Nicolas Coudray, Georgia L Isom, Mark R MacRae, Mariyah N Saiduddin, Gira Bhabha, Damian C Ekiert
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/62518