Temporal Profiling of the Cortical Synaptic Mitochondrial Proteome Identifies Ageing Associated Regulators of Stability

Synapses are particularly susceptible to the effects of advancing age, and mitochondria have long been implicated as organelles contributing to this compartmental vulnerability. Despite this, the mitochondrial molecular cascades promoting age-dependent synaptic demise remain to be elucidated. Here,...

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Bibliographic Details
Main Authors: Laura C. Graham, Rachel A. Kline, Douglas J. Lamont, Thomas H. Gillingwater, Neil A. Mabbott, Paul A. Skehel, Thomas M. Wishart
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/12/3403