BAP1 as a guardian of genome stability: implications in human cancer

Abstract BAP1 is a ubiquitin C-terminal hydrolase domain-containing deubiquitinase with a wide array of biological activities. Studies in which advanced sequencing technologies were used have uncovered a link between BAP1 and human cancer. Somatic and germline mutations of the BAP1 gene have been id...

Full description

Bibliographic Details
Main Authors: Jongbum Kwon, Daye Lee, Shin-Ai Lee
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-00979-1