Hemizygosity for Atm and Brca1 influence the balance between cell transformation and apoptosis
<p>Abstract</p> <p>Background</p> <p>In recent years data from both mouse models and human tumors suggest that loss of one allele of genes involved in DNA repair pathways may play a central role in genomic instability and carcinogenesis. Additionally several examples in...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-02-01
|
| Series: | Radiation Oncology |
| Online Access: | http://www.ro-journal.com/content/5/1/15 |