Longitudinal Monitoring of DNA Viral Loads in Transplant Patients Using Quantitative Metagenomic Next-Generation Sequencing

Longitudinal Monitoring of DNA Viral Loads in Transplant Patients Using Quantitative Metagenomic Next-Generation Sequencing

Introduction: Immunocompromised patients are prone to reactivations and (re-)infections of multiple DNA viruses. Viral load monitoring by single-target quantitative PCRs (qPCR) is the current cornerstone for virus quantification. In this study, a metagenomic next-generation sequencing (mNGS) approac...

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Bibliographic Details
Main Authors: Ellen C. Carbo, Anne Russcher, Margriet E. M. Kraakman, Caroline S. de Brouwer, Igor A. Sidorov, Mariet C. W. Feltkamp, Aloys C. M. Kroes, Eric C. J. Claas, Jutte J. C. de Vries
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pathogens
Subjects:
viral metagenomics
pathogen detection
quantification
next-generation sequencing
load monitoring
Online Access:https://www.mdpi.com/2076-0817/11/2/236

Internet

https://www.mdpi.com/2076-0817/11/2/236

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