Cysteines as Redox Molecular Switches and Targets of Disease

Thiol groups can undergo numerous modifications, making cysteine a unique molecular switch. Cysteine plays structural and regulatory roles as part of proteins or glutathione, contributing to maintain redox homeostasis and regulate signaling within and amongst cells. Not surprisingly therefore, cyste...

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Bibliographic Details
Main Authors: Annamaria Fra, Edgar D. Yoboue, Roberto Sitia
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00167/full