Secondary basophilic leukemia in Ph-negative myeloid neoplasms: A distinct subset with poor prognosis

Secondary basophilic leukemia in Ph-negative myeloid neoplasms: A distinct subset with poor prognosis

During progression of myeloid neoplasms, the basophil compartment may expand substantially and in some of these patients, a basophilic leukemia is diagnosed. In patients with Ph-chromosome+ chronic myeloid leukemia, acceleration of disease is typically accompanied by marked basophilia. In other myel...

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Bibliographic Details
Main Authors: Daniela Berger, Karin Bauer, Christoph Kornauth, Susanne Gamperl, Gabriele Stefanzl, Dubravka Smiljkovic, Christian Sillaber, Peter Bettelheim, Paul Knöbl, Ana-Iris Schiefer, Georg Greiner, Renate Thalhammer, Gregor Hoermann, Ilse Schwarzinger, Philipp B. Staber, Wolfgang R. Sperr, Peter Valent
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Basophils
Basophilic leukemia
IgE receptor
Azacitidine
Venetoclax
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558621000853

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http://www.sciencedirect.com/science/article/pii/S1476558621000853

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