Single-Cell RNA-Seq Analysis Reveals Lung Epithelial Cell Type-Specific Responses to HDM and Regulation by Tet1

Single-Cell RNA-Seq Analysis Reveals Lung Epithelial Cell Type-Specific Responses to HDM and Regulation by Tet1

Tet1 protects against house dust mite (HDM)-induced lung inflammation in mice and alters the lung methylome and transcriptome. In order to explore the role of Tet1 in individual lung epithelial cell types in HDM-induced inflammation, we established a model of HDM-induced lung inflammation in Tet1 kn...

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Bibliographic Details
Main Authors: Tao Zhu, Anthony P. Brown, Lucy P. Cai, Gerald Quon, Hong Ji
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Genes
Subjects:
allergic lung inflammation
Tet1
single-cell RNA-seq
alveolar type 2 (AT2) cells
ciliated cells
Online Access:https://www.mdpi.com/2073-4425/13/5/880

Internet

https://www.mdpi.com/2073-4425/13/5/880

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