Pangenomic Study of Fusobacterium nucleatum Reveals the Distribution of Pathogenic Genes and Functional Clusters at the Subspecies and Strain Levels

Pangenomic Study of Fusobacterium nucleatum Reveals the Distribution of Pathogenic Genes and Functional Clusters at the Subspecies and Strain Levels

ABSTRACT Fusobacterium nucleatum is a prevalent periodontal pathogen and is associated with many systemic diseases. Our knowledge of the genomic characteristics and pathogenic effectors of different F. nucleatum strains is limited. In this study, we completed the whole genome assembly of the 4 F. nu...

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Bibliographic Details
Main Authors: Xiaomei Ma, Tianyong Sun, Jiannan Zhou, Mengfan Zhi, Song Shen, Yushang Wang, Xiufeng Gu, Zixuan Li, Haiting Gao, Pingping Wang, Qiang Feng
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
Fusobacterium nucleatum
pangenomic study
virulence factors
CRISPR types
secondary metabolite biosynthetic gene clusters
Online Access:https://journals.asm.org/doi/10.1128/spectrum.05184-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.05184-22

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