Canolol inhibits gastric tumors initiation and progression through COX-2/PGE2 pathway in K19-C2mE transgenic mice.

4-Vinyl-2, 6-dimethoxyphenol (canolol) is an antioxidant phenolic compound extracted from crude canola oil. In current research, K19-C2mE transgenic mice, developing hyperplastic tumors spontaneously in the glandular stomach, were used to study the mechanisms involved in the anti-inflammation and an...

Full description

Bibliographic Details
Main Authors: Donghui Cao, Jing Jiang, Tetsuya Tsukamoto, Ruming Liu, Lin Ma, Zhifang Jia, Fei Kong, Masanobu Oshima, Xueyuan Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4363315?pdf=render