Lemon‐Derived Extracellular Vesicles Nanodrugs Enable to Efficiently Overcome Cancer Multidrug Resistance by Endocytosis‐Triggered Energy Dissipation and Energy Production Reduction

Lemon‐Derived Extracellular Vesicles Nanodrugs Enable to Efficiently Overcome Cancer Multidrug Resistance by Endocytosis‐Triggered Energy Dissipation and Energy Production Reduction

Abstract Multidrug resistance remains a great challenge for cancer chemotherapy. Herein, a biomimetic drug delivery system based on lemon‐derived extracellular vesicles (EVs) nanodrugs (marked with heparin‐cRGD‐EVs‐doxorubicin (HRED)) is demonstrated, achieving highly efficient overcoming cancer mul...

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Bibliographic Details
Main Authors: Qian Xiao, Wei Zhao, Chentian Wu, Xuejiao Wang, Jianping Chen, Xiubo Shi, Suinan Sha, Jinheng Li, Xiaomei Liang, Yulu Yang, Haoyan Guo, Ying Wang, Jun‐Bing Fan
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Advanced Science
Subjects:
biomimetic nanodrugs
endocytosis
energy dissipation
lemon‐derived extracellular vesicles
multidrug resistance
Online Access:https://doi.org/10.1002/advs.202105274

Internet

https://doi.org/10.1002/advs.202105274

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