Discovery of <i>GLO1</i> New Related Genes and Pathways by RNA-Seq on A2E-Stressed Retinal Epithelial Cells Could Improve Knowledge on Retinitis Pigmentosa

Discovery of <i>GLO1</i> New Related Genes and Pathways by RNA-Seq on A2E-Stressed Retinal Epithelial Cells Could Improve Knowledge on Retinitis Pigmentosa

Endogenous antioxidants protect cells from reactive oxygen species (ROS)-related deleterious effects, and an imbalance in the oxidant/antioxidant systems generates oxidative stress. Glyoxalase 1 (GLO1) is a ubiquitous cellular enzyme involved in detoxification of methylglyoxal (MG), a cytotoxic bypr...

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Bibliographic Details
Main Authors: Luigi Donato, Concetta Scimone, Simona Alibrandi, Giacomo Nicocia, Carmela Rinaldi, Antonina Sidoti, Rosalia D’Angelo
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Antioxidants
Subjects:
<i>GLO1</i>
A2E
oxidative stress
RNA-Seq
retinitis pigmentosa
Online Access:https://www.mdpi.com/2076-3921/9/5/416

Internet

https://www.mdpi.com/2076-3921/9/5/416

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