rWTC‐MBTA Vaccine Induces Potent Adaptive Immune Responses Against Glioblastomas via Dynamic Activation of Dendritic Cells

rWTC‐MBTA Vaccine Induces Potent Adaptive Immune Responses Against Glioblastomas via Dynamic Activation of Dendritic Cells

Abstract Despite strides in immunotherapy, glioblastoma multiforme (GBM) remains challenging due to low inherent immunogenicity and suppressive tumor microenvironment. Converting “cold” GBMs to “hot” is crucial for immune activation and improved outcomes. This study comprehensively characterized a t...

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Bibliographic Details
Main Authors: Herui Wang, Rogelio Medina, Juan Ye, Yaping Zhang, Samik Chakraborty, Alex Valenzuela, Ondrej Uher, Katerina Hadrava Vanova, Mitchell Sun, Xueyu Sang, Deric M. Park, Jan Zenka, Mark R. Gilbert, Karel Pacak, Zhengping Zhuang
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
dendritic cells
glioblastoma
immunotherapy
rWTC‐MBTA vaccine
tumor microenvironment
Online Access:https://doi.org/10.1002/advs.202308280

Internet

https://doi.org/10.1002/advs.202308280

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