Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA

Detection of maternal carriers of common α-thalassemia deletions from cell-free DNA

Abstract α-Thalassemia is a common inherited blood disorder manifested mainly by the deletions of α-globin genes. In geographical areas with high carrier frequencies, screening of α-thalassemia carrier state is therefore of vital importance. This study presents a novel method for identifying female...

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Main Authors: Phuoc-Loc Doan, Duy-Anh Nguyen, Quang Thanh Le, Diem-Tuyet Thi Hoang, Huu Du Nguyen, Canh Chuong Nguyen, Kim Phuong Thi Doan, Nhat Thang Tran, Thi Minh Thi Ha, Thu Huong Nhat Trinh, Van Thong Nguyen, Chi Thuong Bui, Ngoc-Diep Thi Lai, Thanh Hien Duong, Hai-Ly Mai, Pham-Uyen Vinh Huynh, Thu Thanh Thi Huynh, Quang Vinh Le, Thanh Binh Vo, Thi Hong-Thuy Dao, Phuong Anh Vo, Duy-Khang Nguyen Le, Ngoc Nhu Thi Tran, Quynh Nhu Thi Tran, Yen-Linh Thi Van, Huyen-Trang Thi Tran, Hoai Thi Nguyen, Phuong-Uyen Nguyen, Thanh-Thuy Thi Do, Dinh-Kiet Truong, Hung Sang Tang, Ngoc-Phuong Thi Cao, Tuan-Thanh Lam, Le Son Tran, Hoai-Nghia Nguyen, Hoa Giang, Minh-Duy Phan
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17718-7

Internet

https://doi.org/10.1038/s41598-022-17718-7

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