Altered Natural Killer Cell Function in HIV-Exposed Uninfected Infants

Altered Natural Killer Cell Function in HIV-Exposed Uninfected Infants

ObjectivesHIV-exposed uninfected (HEU) infants have higher rates of severe and fatal infections compared with HIV-unexposed (HUU) infants, likely due to immune perturbations. We hypothesized that alterations in natural killer (NK) cell activity might occur in HEU infants and predispose them to sever...

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Bibliographic Details
Main Authors: Christiana Smith, Emilie Jalbert, Volia de Almeida, Jennifer Canniff, Laurel L. Lenz, Marisa M. Mussi-Pinhata, Rachel A. Cohen, Qilu Yu, Fabiana R. Amaral, Jorge Pinto, Jorge O. Alarcon, George Siberry, Adriana Weinberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Immunology
Subjects:
HIV-1
infant
natural killer cells
K562 cells
interleukin-12
respiratory tract infections
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00470/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00470/full

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