Monitoring of Technical Variation in Quantitative High-Throughput Datasets

High-dimensional datasets can be confounded by variation from technical sources, such as batches. Undetected batch effects can have severe consequences for the validity of a study's conclusion(s). We evaluate high-throughput RNAseq and miRNAseq as well as DNA methylation and gene expression mic...

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Bibliographic Details
Main Authors: Martin Lauss, Ilhami Visne, Albert Kriegner, Markus Ringnér, Göran Jönsson, Mattias Höglund
Format: Article
Language:English
Published: SAGE Publishing 2013-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S12862