A Revision of Herpes Simplex Virus Type 1 Transcription: First, Repress; Then, Express

The herpes virus genome bears more than 80 strong transcriptional promoters. Upon entry into the host cell nucleus, these genes are transcribed in an orderly manner, producing five immediate–early (IE) gene products, including ICP0, ICP4, and ICP22, while non-IE genes are mostly silent. The IE gene...

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Bibliographic Details
Main Authors: Laura E. M. Dunn, Claire H. Birkenheuer, Joel D. Baines
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/12/2/262