SARS-CoV-2 Induces Epithelial-Enteric Neuronal Crosstalk Stimulating VIP Release

SARS-CoV-2 Induces Epithelial-Enteric Neuronal Crosstalk Stimulating VIP Release

Background: Diarrhea is present in up to 30–50% of patients with COVID-19. The mechanism of SARS-CoV-2-induced diarrhea remains unclear. We hypothesized that enterocyte–enteric neuron interactions were important in SARS-CoV-2-induced diarrhea. SARS-CoV-2 induces endoplasmic reticulum (ER) stress in...

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Bibliographic Details
Main Authors: Arun Balasubramaniam, Philip R. Tedbury, Simon M. Mwangi, Yunshan Liu, Ge Li, Didier Merlin, Adam D. Gracz, Peijian He, Stefan G. Sarafianos, Shanthi Srinivasan
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomolecules
Subjects:
SARS-CoV-2
diarrhea
enterocytes
enteric neurons
heat shock protein 70
Online Access:https://www.mdpi.com/2218-273X/13/2/207

Internet

https://www.mdpi.com/2218-273X/13/2/207

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