The Inhibition of LPS-Induced Oxidative Stress and Inflammatory Responses Is Associated with the Protective Effect of (-)-Epigallocatechin-3-Gallate on Bovine Hepatocytes and Murine Liver

The Inhibition of LPS-Induced Oxidative Stress and Inflammatory Responses Is Associated with the Protective Effect of (-)-Epigallocatechin-3-Gallate on Bovine Hepatocytes and Murine Liver

This study aimed to evaluate whether (-)-epigallocatechin-3-gallate (EGCG) alleviates hepatic responses to lipopolysaccharide (LPS)-induced inflammation and oxidation. Isolated bovine hepatocytes and BALB/c mice were used for LPS challenge and EGCG pretreatment experiments in vitro and in vivo. LPS-...

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Bibliographic Details
Main Authors: Tianle Xu, Run Liu, Hao Zhu, Yu Zhou, Tianxu Pei, Zhangping Yang
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Antioxidants
Subjects:
EGCG
bovine hepatocytes
hepatoprotective
MAPK/NF-κB signaling
antioxidant activity
Online Access:https://www.mdpi.com/2076-3921/11/5/914

Internet

https://www.mdpi.com/2076-3921/11/5/914

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