Unraveling the intricacies of osteoclast differentiation and maturation: insight into novel therapeutic strategies for bone-destructive diseases

Abstract Osteoclasts are the principal cells that efficiently resorb bone. Numerous studies have attempted to reveal the molecular pathways leading to the differentiation and activation of osteoclasts to improve the treatment and prevention of osteoporosis and other bone-destructive diseases. While...

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Bibliographic Details
Main Authors: Noriko Takegahara, Hyunsoo Kim, Yongwon Choi
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01157-7