Protocol for delivery of intraoperative immunotherapy to mice by surgical debulking of subcutaneous tumors

Summary: Pre-clinical studies developing novel therapies to prevent cancer recurrence require appropriate surgical models. Here, we present a protocol for surgical debulking of subcutaneous tumors in mice, which allows for intraoperative application of immunotherapy-loaded biomaterials. We describe...

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Bibliographic Details
Main Authors: Francois Xavier Rwandamuriye, Breana Vitali, Juliët Schreurs, Tao Wang, Emily Barrick, Killugudi Swaminathan Iyer, Willem Joost Lesterhuis, Rachael M. Zemek, Ben Wylie
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724001138