Cannabinoid receptor 1 positive allosteric modulator (GAT229) attenuates cisplatin-induced neuropathic pain in mice

Cannabinoid receptor 1 positive allosteric modulator (GAT229) attenuates cisplatin-induced neuropathic pain in mice

Chemotherapy-induced peripheral neuropathy (CIPN) is one of chemotherapies’ most often documented side effects. Patients with CIPN experience spontaneous burning, numbness, tingling, and neuropathic pain in their feet and hands. Currently, there is no effective pharmacological treatment to prevent o...

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Bibliographic Details
Main Authors: Amina M. Bagher, Lenah S. Binmahfouz, Rasheed A. Shaik, Basma G. Eid
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Saudi Pharmaceutical Journal
Subjects:
Chemotherapy-induced peripheral neuropathy (CIPN)
GAT229
cisplatin (CIS)
Type 1 cannabinoid receptor (CB1)
Allosteric modulator
dorsal root ganglia (DRG)
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016422003115

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http://www.sciencedirect.com/science/article/pii/S1319016422003115

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