Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

Macrophages are found in tissues, body cavities, and mucosal surfaces. Most tissue macrophages are seeded in the early embryo before definitive hematopoiesis is established. Others are derived from blood monocytes. The macrophage lineage diversification and plasticity are key aspects of their functi...

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Bibliographic Details
Main Authors: Marco Orecchioni, Yanal Ghosheh, Akula Bala Pramod, Klaus Ley
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
macrophage
innate immunity
M1
M2
cancer
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01084/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01084/full

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