SARS‐CoV‐2 N Protein Induces Acute Kidney Injury via Smad3‐Dependent G1 Cell Cycle Arrest Mechanism

SARS‐CoV‐2 N Protein Induces Acute Kidney Injury via Smad3‐Dependent G1 Cell Cycle Arrest Mechanism

Abstract COVID‐19 is infected by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and can cause severe multiple organ injury and death. Kidney is one of major target organs of COVID‐19 and acute kidney injury (AKI) is common in critically ill COVID‐19 patients. However, mechanisms throug...

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Bibliographic Details
Main Authors: Wenbiao Wang, Junzhe Chen, Dingwen Hu, Pan Pan, Liying Liang, Wenjing Wu, Ying Tang, Xiao R. Huang, Xueqing Yu, Jianguo Wu, Hui Y. Lan
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Advanced Science
Subjects:
acute kidney injury
G1 cell cycle
N protein
p21
SARS‐CoV‐2
Smad3
Online Access:https://doi.org/10.1002/advs.202103248

Internet

https://doi.org/10.1002/advs.202103248

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