Resetting histone modifications during human prenatal germline development

Abstract Histone modifications play critical roles in regulating gene expression and present dynamic changes during early embryo development. However, how they are reprogrammed during human prenatal germline development has not yet been elucidated. Here, we map the genome-wide profiles of three key...

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Bibliographic Details
Main Authors: Rui Gao, Shiyang Zeng, Dongxu Yang, Xiaocui Li, Wenqiang Liu, Yawei Gao, Dandan Bai, Linfeng Zhang, Chuan Chen, Yunzhe Kang, Beiying Wang, Wei Hong, Mingzhu Wang, Jiqing Yin, Hong Wang, Qiaolin Deng, Shaorong Gao, Yong Zhang, Jiayu Chen
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-023-00519-1