Chelation of Zinc with Biogenic Amino Acids: Description of Properties Using Balaban Index, Assessment of Biological Activity on <i>Spirostomum Ambiguum</i> Cellular Biosensor, Influence on Biofilms and Direct Antibacterial Action

Chelation of Zinc with Biogenic Amino Acids: Description of Properties Using Balaban Index, Assessment of Biological Activity on <i>Spirostomum Ambiguum</i> Cellular Biosensor, Influence on Biofilms and Direct Antibacterial Action

The complexation of biogenic molecules with metals is the widespread strategy in screening for new pharmaceuticals with improved therapeutic and physicochemical properties. This paper demonstrates the possibility of using simple QSAR modeling based on topological descriptors for chelates study. The...

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Bibliographic Details
Main Authors: Alla V. Marukhlenko, Mariya A. Morozova, Arsène M. J. Mbarga, Nadezhda V. Antipova, Anton V. Syroeshkin, Irina V. Podoprigora, Tatiana V. Maksimova
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceuticals
Subjects:
coordination biochemistry
zinc
methionine
QSAR
Balaban index
biosensor <i>Spirostomum ambiguum</i>
Online Access:https://www.mdpi.com/1424-8247/15/8/979

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https://www.mdpi.com/1424-8247/15/8/979

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