Gene expression study in monocytes: evidence of inflammatory dysregulation in early-onset obsessive-compulsive disorder

Abstract Obsessive-compulsive disorder (OCD) has a complex etiology that seems to include immune dysfunction and alterations in circulating monocytes. To investigate the immune basis and the functional dysregulation of monocytes in this disease, we analyzed gene expression in the peripheral monocyte...

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Bibliographic Details
Main Authors: Natalia Rodríguez, Luisa Lázaro, Ana E. Ortiz, Astrid Morer, Albert Martínez-Pinteño, Alex G. Segura, Patricia Gassó, Sergi Mas
Format: Article
Language:English
Published: Nature Publishing Group 2022-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01905-1