Algorithmic considerations when analysing capture Hi-C data [version 2; peer review: 2 approved]

Chromosome conformation capture methodologies have provided insight into the effect of 3D genomic architecture on gene regulation. Capture Hi-C (CHi-C) is a recent extension of Hi-C that improves the effective resolution of chromatin interactions by enriching for defined regions of biological releva...

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Bibliographic Details
Main Authors: Linden Disney-Hogg, Richard Houlston, Ben Kinnersley
Format: Article
Language:English
Published: Wellcome 2022-11-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/5-289/v2