Structure-guided protein design of fluoroacetate dehalogenase for kinetic resolution of rac-2-bromobutyric acid

R-2-Bromobutyric acid is a very important intermediate for the synthesis of agrochemicals and pharmaceuticals. Bioresolution of rac-2-bromobutyric acid (rac-2-BBA) provides a promising process for R-2-bromobutyric acid (R-2-BBA) production. The fluoroacetate dehalogenase (FAcD) has been always studi...

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Bibliographic Details
Main Authors: Shu Wang, Zhanbing Cheng, Yanbing Xu, Lu Yang, Jian-Bo Wang, Zhenhua Tian, Xudong Qu
Format: Article
Language:English
Published: KeAi Communications Co. Ltd. 2020-06-01
Series:Green Synthesis and Catalysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666554920300041