Activity of PD-1 Inhibitor Combined With Anti-Angiogenic Therapy in Advanced Sarcoma: A Single-Center Retrospective Analysis

Activity of PD-1 Inhibitor Combined With Anti-Angiogenic Therapy in Advanced Sarcoma: A Single-Center Retrospective Analysis

Background: Immune checkpoint inhibitors (ICIs) are employed to treat various cancers, including soft tissue sarcomas (STSs), and less than 20% of patients benefit from this treatment. Vascular endothelial growth factor (VEGF) promotes the immunosuppressive tumor microenvironment and contributes to...

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Bibliographic Details
Main Authors: Yang You, Xi Guo, Rongyuan Zhuang, Chenlu Zhang, Zhiming Wang, Feng Shen, Yan Wang, Wenshuai Liu, Yong Zhang, Weiqi Lu, Yingyong Hou, Jing Wang, Xuan Zhang, Minzhi Lu, Yuhong Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Molecular Biosciences
Subjects:
sarcoma
immunotherapy
anti-angiogenesis
PD-1
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.747650/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2021.747650/full

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