Polar invasion and translocation of Neisseria meningitidis and Streptococcus suis in a novel human model of the blood-cerebrospinal fluid barrier.

Polar invasion and translocation of Neisseria meningitidis and Streptococcus suis in a novel human model of the blood-cerebrospinal fluid barrier.

Acute bacterial meningitis is a life-threatening disease in humans. Discussed as entry sites for pathogens into the brain are the blood-brain and the blood-cerebrospinal fluid barrier (BCSFB). Although human brain microvascular endothelial cells (HBMEC) constitute a well established human in vitro m...

Full description

Bibliographic Details
Main Authors: Christian Schwerk, Thalia Papandreou, Daniel Schuhmann, Laura Nickol, Julia Borkowski, Ulrike Steinmann, Natascha Quednau, Carolin Stump, Christel Weiss, Jürgen Berger, Hartwig Wolburg, Heike Claus, Ulrich Vogel, Hiroshi Ishikawa, Tobias Tenenbaum, Horst Schroten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3256222?pdf=render

Internet

http://europepmc.org/articles/PMC3256222?pdf=render

Similar Items