Piperidine-Iodine as Efficient Dual Catalyst for the One-Pot, Three-Component Synthesis of Coumarin-3-Carboxamides

Piperidine-Iodine as Efficient Dual Catalyst for the One-Pot, Three-Component Synthesis of Coumarin-3-Carboxamides

A simple and efficient one-pot, three-component synthetic method for the preparation of coumarin-3-carboxamides was carried out by the reaction of salicylaldehyde, aliphatic primary/secondary amines, and diethylmalonate. The protocol employs piperidine-iodine as a dual system catalyst and ethanol, a...

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Bibliographic Details
Main Authors: Manuel Velasco, Nancy Romero-Ceronio, Rosalía Torralba, Oswaldo Hernández Abreu, Miguel A. Vilchis-Reyes, Erika Alarcón-Matus, Erika M. Ramos-Rivera, David M. Aparicio, Jacqueline Jiménez, Eric Aguilar García, David Cruz Cruz, Clarisa Villegas Gómez, Cuauhtémoc Alvarado
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
multicomponent reaction
molecular iodine
coumarin-3-carboxamides
Online Access:https://www.mdpi.com/1420-3049/27/14/4659

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https://www.mdpi.com/1420-3049/27/14/4659

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