Niclosamide-loaded nanoparticles (Ncl-NPs) reverse pulmonary fibrosis in vivo and in vitro

Niclosamide-loaded nanoparticles (Ncl-NPs) reverse pulmonary fibrosis in vivo and in vitro

Introduction: Idiopathic pulmonary fibrosis (IPF), a life-threatening interstitial lung disease, is characterized by excessive activation and proliferation of fibroblasts and epithelial-mesenchymal transition (EMT) of alveolar epithelial cells (AEC) accompanied by a large amount of extracellular mat...

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Bibliographic Details
Main Authors: Cailing Gan, Yan Wang, Zhongzheng Xiang, Hongyao Liu, Zui Tan, Yuting Xie, Yuqin Yao, Liang Ouyang, Changyang Gong, Tinghong Ye
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Advanced Research
Subjects:
Idiopathic pulmonary fibrosis
Ncl-NPs
TGF-β/Smad
Stat3
Macrophages
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123222002478

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http://www.sciencedirect.com/science/article/pii/S2090123222002478

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