Pluronic-based nano-self-assemblies of bacitracin A with a new mechanism of action for an efficient in vivo therapeutic effect against bacterial peritonitis

Pluronic-based nano-self-assemblies of bacitracin A with a new mechanism of action for an efficient in vivo therapeutic effect against bacterial peritonitis

Abstract Background Although assemblies of hydrophobic-modified bacitracin A with PLGA (Nano-BAPLGA) have demonstrated promising antibacterial activities against both Gram-positive and Gram-negative bacteria, the desirable antibacterial potency has remained challenging due to the low solubility of N...

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Bibliographic Details
Main Authors: Wei Hong, Lipeng Liu, Yining Zhao, Yinghui Liu, Dexian Zhang, Mingchun Liu
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Journal of Nanobiotechnology
Subjects:
Pluronic-based Nano-BAs
Nano-BAP85
Tensioactive
Membranolytic effect
Efficient therapeutic effect
Online Access:http://link.springer.com/article/10.1186/s12951-018-0397-3

Internet

http://link.springer.com/article/10.1186/s12951-018-0397-3

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