Spatial analysis of expression patterns predicts genetic interactions at the mid-hindbrain boundary.

The isthmic organizer mediating differentiation of mid- and hindbrain during vertebrate development is characterized by a well-defined pattern of locally restricted gene expression domains around the mid-hindbrain boundary (MHB). This pattern is established and maintained by a regulatory network bet...

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Bibliographic Details
Main Authors: Dominik M Wittmann, Florian Blöchl, Dietrich Trümbach, Wolfgang Wurst, Nilima Prakash, Fabian J Theis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19936059/?tool=EBI