Syntaxin 5 is required for copper homeostasis in Drosophila and mammals.

Copper is essential for aerobic life, but many aspects of its cellular uptake and distribution remain to be fully elucidated. A genome-wide screen for copper homeostasis genes in Drosophila melanogaster identified the SNARE gene Syntaxin 5 (Syx5) as playing an important role in copper regulation; fl...

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Bibliographic Details
Main Authors: Melanie Norgate, Adam Southon, Mark Greenough, Michael Cater, Ashley Farlow, Philip Batterham, Ashley I Bush, V Nathan Subramaniam, Richard Burke, James Camakaris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3004795?pdf=render