c-MYC-dependent transcriptional inhibition of autophagy is implicated in cisplatin sensitivity in HPV-positive head and neck cancer

c-MYC-dependent transcriptional inhibition of autophagy is implicated in cisplatin sensitivity in HPV-positive head and neck cancer

Abstract Autophagy is important for the removal, degradation and recycling of damaged organelles, proteins, and lipids through the degradative action of lysosomes. In addition to its catabolic function, autophagy is important in cancer and viral-mediated tumorigenesis, including Human Papillomavirus...

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Bibliographic Details
Main Authors: Alessandro Medda, Micaela Compagnoni, Giorgio Spini, Simona Citro, Ottavio Croci, Stefano Campaner, Marta Tagliabue, Mohssen Ansarin, Susanna Chiocca
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06248-3

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https://doi.org/10.1038/s41419-023-06248-3

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