A Novel Strategy for TNF-Alpha Production by 2-APB Induced Downregulated SOCE and Upregulated HSP70 in O. tsutsugamushi-Infected Human Macrophages.

A Novel Strategy for TNF-Alpha Production by 2-APB Induced Downregulated SOCE and Upregulated HSP70 in O. tsutsugamushi-Infected Human Macrophages.

Orientia (O.) tsutsugamushi-induced scrub typhus is endemic across many regions of Asia and the Western Pacific, where an estimated 1 million cases occur each year; the majority of patients infected with O. tsutsugamushi end up with a cytokine storm from a severe inflammatory response. Previous repo...

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Bibliographic Details
Main Authors: Ching-Ying Wu, Wen-Li Hsu, Chun-Hsiung Wang, Jui-Lin Liang, Ming-Hsien Tsai, Chia-Jung Yen, Hsiu-Wen Li, Siou-Jin Chiu, Chung-Hsing Chang, Yaw-Bin Huang, Ming-Wei Lin, Tohru Yoshioka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4966960?pdf=render

Internet

http://europepmc.org/articles/PMC4966960?pdf=render

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