Priming with Toll-like receptor 3 agonist or interferon-gamma enhances the therapeutic effects of human mesenchymal stem cells in a murine model of atopic dermatitis

Priming with Toll-like receptor 3 agonist or interferon-gamma enhances the therapeutic effects of human mesenchymal stem cells in a murine model of atopic dermatitis

Abstract Background Atopic dermatitis (AD) is a chronic and relapsing inflammatory skin disease. Great efforts have been recently made to treat AD using mesenchymal stem cells (MSCs), which have immunomodulatory functions. However, the immunomodulatory effects of MSCs need to be enhanced for clinica...

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Bibliographic Details
Main Authors: Arum Park, Hyojung Park, Jisun Yoon, Dayeon Kang, Myoung-Hee Kang, Y-Y Park, Nayoung Suh, Jinho Yu
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Priming
Atopic dermatitis
Toll-like receptor 3 agonist
Interferon-γ
Online Access:http://link.springer.com/article/10.1186/s13287-019-1164-6

Internet

http://link.springer.com/article/10.1186/s13287-019-1164-6

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