Serum untargeted lipidomics by UHPLC-ESI-HRMS aids the biomarker discovery of colorectal adenoma

Serum untargeted lipidomics by UHPLC-ESI-HRMS aids the biomarker discovery of colorectal adenoma

Abstract Background Colorectal adenoma (CA) is an important precancerous lesion and early screening target of colorectal cancer (CRC). Lipids with numerous physiological functions are proved to be involved in the development of CRC. However, there is no lipidomic study with large-scale serum samples...

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Bibliographic Details
Main Authors: Hailin Zhou, Yanying Nong, Yifan Zhu, Yunxiao Liang, Jiahao Zhang, Hongwei Chen, Pingchuan Zhu, Qisong Zhang
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Cancer
Subjects:
Colorectal adenoma
Biomarkers
Serum lipidomics
Early screening
UHPLC-ESI-HRMS
Colorectal cancer
Online Access:https://doi.org/10.1186/s12885-022-09427-1

Internet

https://doi.org/10.1186/s12885-022-09427-1

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