An information-theoretic characterization of the optimal gradient sensing response of cells.

Many cellular systems rely on the ability to interpret spatial heterogeneities in chemoattractant concentration to direct cell migration. The accuracy of this process is limited by stochastic fluctuations in the concentration of the external signal and in the internal signaling components. Here we u...

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Bibliographic Details
Main Authors: Burton W Andrews, Pablo A Iglesias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1937015?pdf=render