Case report: Temozolomide induced hypermutation indicates an unfavorable response to immunotherapy in patient with gliomas

BackgroundTemozolomide (TMZ) is a key component in the treatment of gliomas. Hypermutation induced by TMZ can be encountered in routine clinical practice, and its significance is progressively gaining recognition. However, the relationship between TMZ-induced hypermutation and the immunologic respon...

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Bibliographic Details
Main Authors: Jiapeng Liu, Shuli Hu, Haihui Jiang, Yong Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1369972/full