Translation levels control multi-spanning membrane protein expression.

Attempts to express eukaryotic multi-spanning membrane proteins at high-levels have been generally unsuccessful. In order to investigate the cause of this limitation and gain insight into the rate limiting processes involved, we have analyzed the effect of translation levels on the expression of sev...

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Bibliographic Details
Main Authors: Hok Seon Kim, James A Ernst, Cecilia Brown, Jenny Bostrom, Germaine Fuh, Chingwei V Lee, Arthur Huang, Richard L Vandlen, Daniel G Yansura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338534?pdf=render