Preparation of Idebenone as a Thermosetting Nasal Gel for Better Bioavailability and Histopathological Effect
Background Idebenone is an extensively metabolized drug with poor water solubility that is used to treat Leiber’s hereditary optical neuropathy. Objective This study aims to prepare idebenone nanoemulsion as a poloxamer-based nasal gel to overcome the extensive rate of hepatic metabolism for bett...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
College of Medicine University of Baghdad
2023-10-01
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Series: | مجلة كلية الطب |
Subjects: | |
Online Access: | https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/2082 |