Preparation of Idebenone as a Thermosetting Nasal Gel for Better Bioavailability and Histopathological Effect

Background Idebenone is an extensively metabolized drug with poor water solubility that is used to treat Leiber’s hereditary optical neuropathy. Objective This study aims to prepare idebenone nanoemulsion as a poloxamer-based nasal gel to overcome the extensive rate of hepatic metabolism for bett...

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Bibliographic Details
Main Authors: Hussein Jaafer, Khalid Kadhem Al-Kinani
Format: Article
Language:English
Published: College of Medicine University of Baghdad 2023-10-01
Series:مجلة كلية الطب
Subjects:
Online Access:https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/2082