Knockdown of KDM5B Leads to DNA Damage and Cell Cycle Arrest in Granulosa Cells via MTF1

KDM5B is essential for early embryo development, which is under the control of maternal factors in oocytes. Granulosa cells (GCs) play a critical role during oocyte mature. However, the role of KDM5B in GCs remains to be elucidated. In the current study, we found that KDM5B expressed highly in the o...

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Bibliographic Details
Main Authors: Yingnan Yang, Yu Cai, Jinjing Guo, Keke Dai, Liang Liu, Zili Chen, Feng Wang, Mingtian Deng
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/45/4/210