Peroxisomal compartmentalization of amino acid biosynthesis reactions imposes an upper limit on compartment size

Abstract Cellular metabolism relies on just a few redox cofactors. Selective compartmentalization may prevent competition between metabolic reactions requiring the same cofactor. Is such compartmentalization necessary for optimal cell function? Is there an optimal compartment size? Here we probe the...

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Bibliographic Details
Main Authors: Ying Gu, Sara Alam, Snezhana Oliferenko
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41347-x