Upregulation of carbonic anhydrase 1 beneficial for depressive disorder

Upregulation of carbonic anhydrase 1 beneficial for depressive disorder

Abstract Carbonic Anhydrase 1 (CAR1) is a zinc-metalloenzyme that catalyzes the hydration of carbon dioxide, and the alteration of CAR1 has been implicated in neuropsychiatric disorders. However, the mechanism underlying the role of CAR1 in major depressive disorder (MDD) remains largely unknown. In...

Full description

Bibliographic Details
Main Authors:	Ke Cheng, Yue Wang, Yong He, Yu Tian, Junjie Li, Chong Chen, Xingzhe Xu, Zhonghao Wu, Heming Yu, Xiangyu Chen, Yili Wu, Weihong Song, Zhifang Dong, Huatai Xu, Peng Xie
Format:	Article
Language:	English
Published:	BMC 2023-04-01
Series:	Acta Neuropathologica Communications
Subjects:	Carbonic anhydrase 1 Hippocampal astrocytes Miniature inhibitory postsynaptic currents CAR1-knockout mice Major depressive disorder
Online Access:	https://doi.org/10.1186/s40478-023-01545-6

Similar Items

Genetic background determines synaptic phenotypes in Arid1b-mutant mice
by: Hyosang Kim, et al.
Published: (2024-03-01)

Key Metabolic Enzymes Underlying Astrocytic Upregulation of GABAergic Plasticity
by: Przemysław T. Kaczor, et al.
Published: (2017-05-01)

Differential synaptic mechanism underlying the neuronal modulation of prefrontal cortex, amygdala, and hippocampus in response to chronic postsurgical pain with or without cognitive deficits in rats
by: Zhen Li, et al.
Published: (2022-09-01)

Synedrella nodiflora Extract Depresses Excitatory Synaptic Transmission and Chemically-Induced In Vitro Seizures in the Rat Hippocampus
by: Patrick Amoateng, et al.
Published: (2021-03-01)

Excitatory and inhibitory receptors utilize distinct post- and trans-synaptic mechanisms in vivo
by: Taisuke Miyazaki, et al.
Published: (2021-10-01)

Excitatory actions of GABA in the intact neonatal rodent hippocampus in vitro
by: Guzel eValeeva, et al.
Published: (2013-03-01)

Differential Effects of Alpha 1-Adrenoceptor Antagonists on the Postsynaptic Sensitivity: Using Slice Patch-Clamp Technique for Inhibitory Postsynaptic Current in Substantia Gelatinosa Neurons From Lumbosacral Spinal Cord in Rats
by: Daisuke Uta, et al.
Published: (2020-06-01)

Carbonic Anhydrase 1-Mediated Calcification Is Associated With Atherosclerosis, and Methazolamide Alleviates Its Pathogenesis
by: Lin Yuan, et al.
Published: (2019-07-01)

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy
by: Teresa Ravizza, et al.
Published: (2008-01-01)

Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism
by: Omar Babateen, et al.
Published: (2017-12-01)

Nitrous anhydrase activity of carbonic anhydrase II: cysteine is required for nitric oxide (NO) dependent phosphorylation of VASP in human platelets
by: Dimitrios Tsikas, et al.
Published: (2021-01-01)

Patch-clamp recordings of thermal effects of magnetic stimulation on the physiological characteristic of rat hippocampal neurons
by: Zheng Yu, et al.
Published: (2016-01-01)

Selectivity of Monaural Synaptic Inputs Underlying Binaural Auditory Information Integration in the Central Nucleus of Inferior Colliculus
by: Jinxing Wei, et al.
Published: (2018-10-01)

Lithium ameliorates autistic-like behaviors induced by neonatal isolation in rats
by: Xiaoyan eWu, et al.
Published: (2014-06-01)

Click chemistry approaches for developing carbonic anhydrase inhibitors and their applications
by: Andrea Angeli, et al.
Published: (2023-12-01)

Roles of Carbonic Anhydrases and Carbonic Anhydrase Related Proteins in Zebrafish
by: Ashok Aspatwar, et al.
Published: (2022-04-01)

Deprivation of Muscleblind-Like Proteins Causes Deficits in Cortical Neuron Distribution and Morphological Changes in Dendritic Spines and Postsynaptic Densities
by: Kuang-Yung Lee, et al.
Published: (2019-07-01)

Astrocytes Are Involved in the Effects of Ketamine on Synaptic Transmission in Rat Primary Somatosensory Cortex
by: Jie Yuan, et al.
Published: (2023-08-01)

A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology
by: Benjamin FN Campbell, et al.
Published: (2022-10-01)

Building up the inhibitory synapse
by: Enrico eCherubini, et al.
Published: (2013-01-01)

Five-Membered Heterocyclic Sulfonamides as Carbonic Anhydrase Inhibitors
by: Andrea Angeli, et al.
Published: (2023-04-01)

Biochemical and in silico inhibition of bovine and human carbonic anhydrase-II by 1H-1,2,3-triazole analogs
by: Majid Khan, et al.
Published: (2022-11-01)

Carbonic Anhydrases: Role in pH Control and Cancer
by: Mam Y. Mboge, et al.
Published: (2018-02-01)

Ureidobenzenesulfonamides as Selective Carbonic Anhydrase I, IX, and XII Inhibitors
by: Toni C. Denner, et al.
Published: (2023-11-01)

Synthesis of New 1H-1,2,3-Triazole Analogs in Aqueous Medium via “Click” Chemistry: A Novel Class of Potential Carbonic Anhydrase-II Inhibitors
by: Satya Kumar Avula, et al.
Published: (2021-06-01)

The Structural Basis of Long-Term Potentiation in Hippocampal Synapses, Revealed by Electron Microscopy Imaging of Lanthanum-Induced Synaptic Vesicle Recycling
by: John E. Heuser
Published: (2022-08-01)

Deletion of LRP1 From Astrocytes Modifies Neuronal Network Activity in an in vitro Model of the Tripartite Synapse
by: Ramona Romeo, et al.
Published: (2021-01-01)

Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome
by: Alexander M. Kleschevnikov, et al.
Published: (2012-02-01)

Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis
by: Ning-Ning Song, et al.
Published: (2017-06-01)

Identification and characterization of a novel zebrafish (Danio rerio) pentraxin–carbonic anhydrase
by: Maarit S. Patrikainen, et al.
Published: (2017-12-01)

Dioxygen, an unexpected carbonic anhydrase ligand
by: Marta Ferraroni, et al.
Published: (2018-01-01)

Integrative Transcriptomic Analyses of Hippocampal–Entorhinal System Subfields Identify Key Regulators in Alzheimer's Disease
by: Dan Luo, et al.
Published: (2023-08-01)

D-serine and serine racemase are associated with PSD-95 and glutamatergic synapse stability
by: Hong eLin, et al.
Published: (2016-02-01)

The increased of carbonic anhydrase in liver tissue of rat induced by chronic systemic hypoxia
by: Rahmawati Ridwan, et al.
Published: (2018-06-01)

Carbonic Anhydrases and Their Biotechnological Applications
by: Robert McKenna, et al.
Published: (2013-08-01)

The effect of carbonic anhydrase IX on focal contacts during cell spreading and migration.
by: Lucia eCsaderova, et al.
Published: (2013-10-01)

Chromene-Containing Aromatic Sulfonamides with Carbonic Anhydrase Inhibitory Properties
by: Andrea Angeli, et al.
Published: (2021-05-01)

Functional maps of neocortical local circuitry
by: Alex M Thomson, et al.
Published: (2007-10-01)

CARBONIC ANHYDRASE AS A MARKER OF OSTEOCLAST ACTIVITY IN THE REPAIR ZONE OF LONG BONE FRACTURE
by: I. A. Shurygina, et al.
Published: (2012-09-01)

Carbonic anhydrase activity in the red blood cells of sea level and high altitude natives
by: JORGE GAMBOA, et al.
Published: (2000-01-01)