Advances in the Genetics of Hypertension: The Effect of Rare Variants

Advances in the Genetics of Hypertension: The Effect of Rare Variants

Worldwide, hypertension still represents a serious health burden with nine million people dying as a consequence of hypertension-related complications. Essential hypertension is a complex trait supported by multifactorial genetic inheritance together with environmental factors. The heritability of b...

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Bibliographic Details
Main Authors: Alessia Russo, Cornelia Di Gaetano, Giovanni Cugliari, Giuseppe Matullo
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
essential hypertension
blood pressure
genome-wide association studies
exome microarray
next-generation sequencing
rare variants
rare-variants association testing
burden test
sequence kernel association test
Online Access:http://www.mdpi.com/1422-0067/19/3/688

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http://www.mdpi.com/1422-0067/19/3/688

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