Mechanistic and single-dose in vivo therapeutic studies of Cry5B anthelmintic action against hookworms.

Hookworm infections are one of the most important parasitic infections of humans worldwide, considered by some second only to malaria in associated disease burden. Single-dose mass drug administration for soil-transmitted helminths, including hookworms, relies primarily on albendazole, which has var...

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Bibliographic Details
Main Authors: Yan Hu, Bin Zhan, Brian Keegan, Ying Y Yiu, Melanie M Miller, Kathryn Jones, Raffi V Aroian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3493396?pdf=render