Mechanistic and single-dose in vivo therapeutic studies of Cry5B anthelmintic action against hookworms.

<h4>Background</h4>Hookworm infections are one of the most important parasitic infections of humans worldwide, considered by some second only to malaria in associated disease burden. Single-dose mass drug administration for soil-transmitted helminths, including hookworms, relies primaril...

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Bibliographic Details
Main Authors: Yan Hu, Bin Zhan, Brian Keegan, Ying Y Yiu, Melanie M Miller, Kathryn Jones, Raffi V Aroian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001900&type=printable