CCL18 promotes breast cancer progression by exosomal miR-760 activation of ARF6/Src/PI3K/Akt pathway

CCL18 promotes breast cancer progression by exosomal miR-760 activation of ARF6/Src/PI3K/Akt pathway

The small GTPase ADP-ribosylation factor 6 (ARF6) mediates chemokine (C-C motif) ligand 18 (CCL18)-induced activation of breast cancer (BC) metastasis through its downstream effector AMAP1. However, the molecular mechanisms underlying CCL18 up-regulating ARF6 remain largely unclear. Here, microRNAs...

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Bibliographic Details
Main Authors: Xiaojia Huang, Shengqing Lai, Fanli Qu, Zongyan Li, Xiaoyan Fu, Qian Li, Xiaofang Zhong, Chao Wang, Haiyan Li
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
breast cancer
exosome
CCL18
miR-760
ARF6/Src/PI3K/Akt signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770522000468

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http://www.sciencedirect.com/science/article/pii/S2372770522000468

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